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Meta
The Rundown AI: “Spatial Intelligence”
| AI ‘godmother’ advocates for spatial intelligence |
Image source: Reve / The Rundown |
| The Rundown: Famed AI specialist Dr. Fei-Fei Li just published a new essay detailing why the next breakthrough in AI will come from spatial intelligence, or systems that can understand, reason about, and generate 3D, physics-consistent worlds. |
| The details: |
| Li argues that while LLMs have mastered abstract knowledge, they lack the ability to perceive and act in space (things like estimating distance and motion).She said spatial understanding is the cognitive core of human intelligence and a crucial step to take AI from language to perception and action.World models, Li said, will be key to building this intelligence, but they need the ability to create realistic 3D worlds, understand inputs like images and actions, and predict how those worlds change over time.She added that these models will ultimately unlock new advances in robotics, science, healthcare, and design by enabling AI to reason in the real world. |
| Why it matters: World models that understand how objects move and interact could one day predict molecular reactions, model climate systems, or test materials. The challenge lies in teaching AI real-world physics, but momentum is building fast with Li’s World Labs, Google, and Tencent all racing to bring spatially intelligent systems to life. |
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Eddie Hobbs: Climate change. What do we really know? Very little … for instance a volcano in the deep sea caused the rising in climate pattern in 2023 2024
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The Deep View: EU could loosen privacy, tech regulations
EU could loosen privacy, tech regulations |
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| The European Union might be rolling back its red tape. |
| The European Commission will unveil a “digital omnibus” package in late November, according to POLITICO, aimed at simplifying its tech and privacy laws. The amendments include broad changes to the General Data Protection Regulation, the EU’s strict rules governing individuals’ control over their personal data. |
| The move could open doors for tech giants seeking to grow their AI footprint in Europe, something which model providers are already ramping up to do. |
| Bloomberg reported in late October that ChatGPT Enterprise adoption is up sixfold year-over-year in Europe, the Middle East and Africa. As part of its broader international expansion, Anthropic last week announced new offices in Paris and Munich. The company noted in a press release that the region has become its fastest-growing market, with customers representing more than $100,000 in run-rate revenue growing ten times over the past year. |
| The move could also help strengthen homegrown AI in the region. While the EU has a few stand-out AI firms, such as Mistral AI and DeepL, the region has largely struggled to keep pace with the rapid development of U.S. and Chinese firms. |
| This move is not the region’s first attempt to try and compete. In early October, EU officials outlined two plans to boost AI adoption and research, and announced a $1.1 billion investment in doing so. The plans specifically target European workforces adopting the tech and raising the profile of the EU’s AI-powered scientific research. |
| And following pressure from the Trump administration and Big Tech, the European Commission is also reportedly weighing plans to delay parts of the EU AI Act, a landmark initiative to rein in AI development that could pose a risk to people’s safety, offering a yearlong “grace period” to companies that break these rules. |
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| The EU differs from the U.S. and China in one main way: stringent tech regulation that protects people over companies. The region has largely prioritized data security and safety over moving fast and breaking things, as evidenced by the EU AI Act’s passing in the first place. Upending the GDPR marks a stark 180 in the region’s approach to AI regulation thus far — and its tech policy strategy as a whole — potentially signalling a shift in priorities as the tech continues its rapid ascent. |
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Tagged ai, artificial-intelligence, business, news, technology
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New Atlas: New target to prevent Alzheimer’s patients forgetting loved ones
New target to prevent Alzheimer’s patients forgetting loved ones
November 10, 2025

Researchers are studying how changes in the brain may cause Alzheimer’s patients to forget loved ones, and exploring new ways to prevent memory loss
Illustration by John DiJulio/University Communications
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New research has found that the loss of social memory – recognizing friends and family – in Alzheimer’s disease (AD) could come down to specific structures around brain cells. And targeting this delicate scaffolding may potentially prevent this heartbreaking stage in cognitive decline.
Scientists from the University of Virginia (UVA) School of Medicine first discovered the role these structures – known as perineural nets – play in AD neurodegeneration in July 2024, and the team has now demonstrated that the loss of these structures disrupts the brain’s ability to recall social connections.
“Finding a structural change that explains a specific memory loss in Alzheimer’s is very exciting,” said Sontheimer, chair of UVA’s Department of Neuroscience and member of the UVA Brain Institute. “It is a completely new target, and we already have suitable drug candidates in hand.”

Sontheimer and team believed that disruptions in these perineural nets, which protect communicating nerve cells, result in the neurons being unable to form and store memories. While perineuronal nets were first discovered back in 1898 by Camillo Golgi, the UVA scientists believe these structures are a lot more important to our brain’s health than previously thought. These nets surround inhibitory neurons, which play a key role in regulating brain activity, slowing down the signals transmitted by excitatory nerve cells.
When the nets are damaged through AD, specialized support cells (astrocytes) cease being able to remove potassium or glutamate from the synapse that connects the neurons, which then causes glutamate to “spill over” into regions it shouldn’t be, potentially killing off neighboring neurons.
In a mouse model, the researchers found that damaged perineural nets resulted in the animals losing their “social memory,” unable to recognize mice they were familiar with – even though other parts of their memory and object recognition was intact. This is, of course, something that occurs as AD progresses, where patients can fail to identify loved ones yet retain “object memory” for some time. When the scientists kept the perineural nets intact, mice were able to recognize familiar animals.
“In our research with mice, when we kept these brain structures safe early in life, the mice suffering from this disease were better at remembering their social interactions,” said graduate student Lata Chaunsali. “Our research will help us get closer to finding a new, nontraditional way to treat or, better yet, prevent Alzheimer’s disease, something that is much needed today.”
The team used matrix metalloproteinase (MMP) inhibitors – which are predominantly being investigated in cancer research – to block the AD-driven damage to perineural nets in mice, and the treatment halted their destruction. While still early days, these existing drugs could be an entirely new way to protect the brain as the disease progresses.
“Although we have drugs that can delay the loss of perineuronal nets, and thereby delay memory loss in disease, more research needs to be done regarding safety and effectiveness of our approach before this can be considered in humans,” Sontheimer said. “One of the most interesting aspects of our research is the fact that the loss of perineuronal nets observed in our studies occurred completely independent of amyloid and plaque pathology, adding to the suspicion that those protein aggregates may not be causal of disease.”
The research was published in the journal Alzheimer’s & Dementia.
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Tagged alzheimers-disease, dementia, health, mental-health, neuroscience
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@MarioNawfal: AI TO THE RESCUE: UK TRIALS SAME-DAY PROSTATE CANCER DIAGNOSES

AI TO THE RESCUE: UK TRIALS SAME-DAY PROSTATE CANCER DIAGNOSES
Waiting weeks for a prostate cancer diagnosis? That’s cute. The UK Health Service is now testing AI that scans MRIs in minutes – fast-tracking high-risk cases to radiologists and booking same-day biopsies. 15 hospitals are in on the trial, and if it works, men could dodge months of anxious limbo while the system catches up. Wes Streeting calls it a revolution. For once, he might be right. Source: Sky News
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Mario Nawfal

@MarioNawfal
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Oct 21
GENETICALLY WIRED FOR WORSE CANCER? NEW DRUG COMBO BUYS TIME If your prostate cancer comes with BRCA or similar DNA repair mutations, it usually means faster spread and fewer options. But a global study found that adding niraparib – a smart drug that exploits those broken x.com/MarioNawfal/st…
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@MarioNawfal: “4 EASTERN EUROPEAN COUNTRIES SAY “HELL NO” TO EU’S 90% EMISSIONS CUT PLAN

4 EASTERN EUROPEAN COUNTRIES SAY “HELL NO” TO EU’S 90% EMISSIONS CUT PLAN
Poland, Hungary, Czechia & Slovakia just told Brussels “no thanks” to a new plan forcing a 90% cut in greenhouse gas emissions by 2040. The rest of the EU? Mostly on board, 21 countries backed it, while Belgium and Bulgaria quietly hit “maybe later.”
The 4 countries isn’t buying it. They say the costs are insane, the rules are rigid, and the whole thing could gut what’s left of Europe’s industrial edge. It still needs to get through the EU Parliament, but if you thought America’s climate politics were spicy, wait ‘til you see Eastern Europe’s take on green utopia. Source: Financial Times, EU Council
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Image source: Reve / The Rundown

