Leading COVID Vaccine Candidates Plagued by Safety Concerns

The Most Revolutionary Act

Unproven technologies, unsafe ingredients and inadequate testing — fortunately, current law prohibits mandating unlicensed vaccines approved for “emergency use.”

“It works!” trumpeted the normally stoic Nature journal about Pfizer’s early release results in a Phase III trial of its vaccine for COVID-19. Pfizer stated the vaccine was 90% effective when trial participants were exposed to SARS CoV-2, the virus said to cause COVID-19 symptoms.

Not so fast. Pfizer’s study protocol states cases count even if a trial participant has a positive test and only one symptom — like a cough, chills or diarrhea — that could easily be caused by one of 1,400 human pathogens, including 200 viruses known to infect humans. Except for Hepatitis A, B, C and HIV, the study protocol is silent on testing for other infectious causes of the participant’s symptoms.

In other words, the study suffers…

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Media Multitasking Is Ruining Our Memory. Can We Fix It?

Remembering something is a complicated problem for the brain. First, you have to encode the memory into your neural networks; then it has to stick around.

Source: Media Multitasking Is Ruining Our Memory. Can We Fix It?

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A day in the Life … during Ireland’s second Lockdown introduced Midnight 23rd October 2020: COVID-19 has its stranglehold on the people of the global landmass; it is a virus that has the potential to kill especially those who are elderly or vulnerable to medical conditions. It is essential for all people to change their behaviours; these behaviours have centuries of history behind them; they are basic; we have no vaccine yet.

Groundhog day life: it is worth a thought that there are people who live Groundhog day because they were born with a disability, have sustained a long term brain injury, those who have lived their lives and are now elderly, and there many exemplary situations which can help people to change their behaviours to live as we must with the virus COVID-19 until a vaccine is available and that could be in 2021, 2022; the real truth is that we must realise that there may be no vaccine. I live Groundhog Day – abiding by a rigid routine because cognitive impairment means that memories formed enter oblivion but I learned to cope through routine and using the benefits of a technology.

The Pandemic has caused a an acceleration and change is thrust upon us and the challenge is to engage. Part of my rehabilitation over the last 30 years has been caterpulted to near “normal” because of these advances in technology hence I can write on WordPress, publish a book on Amazon and everyday I use Twitter to re-engage from an empty brain to hook up with society. Some people use Twitter daily to upload famous paintings; other’s historical events; others are politics fanatics; others just chit chat. We will ignore those who are trolls. I use “Twitter to augment my memory” as do others who have sustained a brain injury or stroke. Everyday I seek out a quote that may be appropriate to news on that day. I then look for quotations that may be relevant and I send them at random to people I think may be interested in them.

I was talking to two interesting people who lived in South Korea and we discussed the differences in culture. Breaking rules is part of our culture in Ireland having been subjugated to colonial rule for over 700 years, hence there are sound historic reasons for this. China differs. we talk about Autocracy of the ruling elite but in reality it is more to do with the word “Altruism” and the ordinary majority of people; Confucius thinking prevails and the Chinese people tend to and aspire to take account of others so that when it was understood that the masks would benefit other people; they adapted promptly and masks were worn; they were a priority because by wearing a mask you ensure the virus will not pass to other people who are in your company.

Instead I will meander through an experience that is not yet one year old and that is COVID-19 and how it has impacted on a global scale beyond all human comprehension. I will start with the two major players, China and the United States of America, one an ancient culture and aspirational to be the leader again and the United States of America, the assumed Guardian of the weaker countries in the world and possibly losing territory. They share in that both have experienced pandemics within the last 100 years, in America in 1918 there was The Great Influenza which travelled by rail and boat globally killing somewhere between 50 and 100 million people, more than the number killed in World War I 1914-18. China 2020 Wuhan, Hubei province SARS.CoV.2, the disease COVID-19, a zoonotic transmission from animal to human and then passed from human to human.

Everyday I choose a tweet with a quote and often a comment:-

Tweet @canisgallicus

Autumnal & beautiful. Not a reprimand but a suggestion. Leeson Street, Dublin 2 pupils gathered in huddles unaware of realities of COVID-19; “Tell people – and they may forget… show them – they may remember… but involve them and they will understand.” Confucius

Tell people – and they may forget

Show them – they may remember

BUT involve them and they will understand

Confucius 551-479 BC

Confucius “Master Kǒng”; 551–479 BC) was a Chinese philosopher and politician of the Spring and Autumn period. Confucius founded the Confucian (Confucianism) school of thinking. It emphasized personal and governmental morality, correctness of social relationships, justice, kindness, and sincerity. While Confucians emphasize personal cultivation of character, they give priority not to the individual but to the family, community, and the world. The Confucian approach to learning and education, which emphasizes humanity and service to others, is of significant value to the modern world. The emphasis of Confucian learning is on the search for personal strength and the commitment to social responsibility. Confucius believed in the equality and educability of all people. He viewed education as a means of transformation, the discovery of human nature, and the cultivation of character.

Globalisation opened up trade between countries and trading blocs like the US, UK, EU, South America, Africa, Middle East, Asia (and they have strong links forged with Russia) to each other. What is interesting at this point is to note China’s Confucian belief system and how they have established Confucian Institutes in countries especially the US, where their interaction is already attracting attention. Universities in America welcome large tranches of investment from overseas and exchange programmes especially in the area of research. They have accepted Confucian Institutes attached to many of their most prestigious universities. However, President Trump won the 2016 election using the slogan “Make America Great Again”; it was about getting American people back into the workforce and encouraging companies based abroad, often for tax purposes, to return to the US and create the much needed employment. China became a target. https://www.globaltimes.cn/content/1200100.shtml Today we await the result of the November 3rd, 2020 US election to know if President Trump will continue in office or will it be Biden?

1918 was the year of The Great Influenza, starting in the US and spreading throughout the world. Between 50 million and 100 million people died; it was more than the number of people killed in World War II. December 2019, it was Wujan, Hubei province China that resulted in the present day pandemic SARS-CoV-2, known as COVID-19; it is the re-emergence of the coronavirus. The difference this time was that the information was delayed; a holiday involved people travelling and spreading the virus and this time it was by way airline travel. No borders just a massive spread throughout the global population.

Marching Plague, Germ warfare and Global Pandemic by Critical Art Ensemble. Why? Because we need to know about Bioterrorism and its potential in the 21st century. COVID-19 is a pandemic but the following quotation explains that the source of terror can be orchestrated in a laboratory too. It is Bioterrorism that incurs Military Industrial Complex funding which could be used to fund an adequate and proper public health system especially in the US, which is in chaos as a result of COVID-19 and sustaining economic lockdowns that have forced into a recesssion that is predicted to be a depression comparable to that in the 1930’s.

A press release from the University of Pittsburgh Medical Centre:-

Bioterrorism is the greatest national security threat of the 21st Century. Bioweapons attacks could cause death and suffering on a catastrophic scale, wreak enormous economic and social disruption, and even threaten core democratic processes. Adequate defence does not depend on our military strength but on medical and public health systems and availability of effective drugs and vaccines….(Critical Art Ensemble pg 18).

COVID-19 is not an act of bioterrorism; but its impact and its implications socially, economically and to the health of people, are playing out each hour of every day in every country and continent in real time. What we can assume is that there are “Preparedness Plans” in place. We know diseases like smallpox, measles, mumps, rubella have caused many deaths but vaccines through expertise and specialised medical endeavours, and a proactive system of public health, have ensured that people are inoculated and therefore will not die from these viruses. What COVID-19 warns us is that the improbability of germ warfare and the over-spending on research into same leaves public health underfunded for research into diseases that kill millions of people every year. Not since the 1960’s has there been significant pressure from citizen groups and scientific professionals to end germ warfare programs (Central Art Ensemble pg 40)

Communism is the nucleus of the politics of China; and Capitalism is core to the doctrine of the democracy of the US. The irony is the Pandemic COVID-19 is beyond borders. China is moving hundred’s of millions out of sheer poverty and this aided by trade deals with other countries especially the US which was facilitated by a move by countries from protectionism to globablisation. However what we do know is that capitalism in the US directed funds which would otherwise have been spent in public health into the war machine and this is now challenged and could result in a change beyond expectations for what is medical health provision in the US and a system of proper health made available to all citizens of the country without having to pay; as is the practice in the UK through the NHS and in many EU countries. Health surely is a basic human right. We can learn from Cuba’s health system which is free to all and who send their medical teams to disaster locations all over the world as an intervention team.

Capitalism has a major faultline and that is the production of poverty. Too often people are packed together in ghettos; there is improper water and sewage treatment. Capitalism unsupervised mindlessly eliminates surplus populations by “sheer neglect”., Central Art Ensemble, (pg 101) Capitalism has created the engines of growth to eliminate such poverty by a fairer redistribution of wealth but that the reality in First World countries, in particular, is that thatengine of growth is for the wealthy and not the poor who outnumber the weatlhy.

I have selected this quotation from Gore Vidal because he clearly makes the statement that monothesism although embedded in our world, causing military interventions and hostilities throughout the world, in favour of Confucianism, which as he says “is not a religion but an “ethical and educational system”.

“I regard monotheism as the greatest disaster ever to befall the human race. I see no good in Judaism, Christianity, or Islam – good people, yes, but any religion based on a single, well, frenzied and virulent god, is not as useful to the human race as, say, Confucianism, which is not a religion but an ethical and educational system. Gore Vidal

Is this why “containment of the virus” was so successful in the Asian countries? Is this why the capitalist driven, extremely wealthy physicians lose faith in their mission in life and as many as one lecture theatre in a university, commit suicide each year. It would be interesting to know about doctors and suicide in China? The word “vocation” to working in the health system in most first world countries is long forgotten and without a vocation or a Confucian belief system medicine fails to reward people with wealth as its only driving force.

Sir Angus Deaton; Anne Case coined the expression “Deaths of Despair…the end of Capitalism” https://www.youtube.com/watch?v=yXf-xcR8bdA

Physicians/Doctors who commit suicide: To mother, a nurse and her little 7 month old baby who died today. We must learn to understand people; not to stigmatise them or shame them. https://www.ted.com/talks/dominic_king_physician_suicide_what_medical_students_need_to_know/up-next

Hope: Greek Prime Minister talking with Yuval Noah Harari 4th October 2020 https://www.youtube.com/watch?v=FjUyZLvFGuw

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Book: “Fortune Favours the Brave”

by Michelle Marcella Clarke

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Keep your mask on: Why a coronavirus vaccine won’t be the panacea many hope for – Bulletin of the Atomic Scientists

We all want the pandemic to end. Many of us are are hoping a coronavirus vaccine becomes available soon. But will a vaccine development process that many believe has been politicized and some fear is being rushed deliver a safe and effective vaccine? Will people want to take it? As we wait to breath a sigh of relief, we’ll still need to keep those masks handy.

Source: Keep your mask on: Why a coronavirus vaccine won’t be the panacea many hope for – Bulletin of the Atomic Scientists

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Estonia Is a ‘Digital Republic’—What That Means and Why It May Be Everyone’s Future

Estonia has digitized 99 percent of its public services and persistently achieves one of the highest ratings of trust in government in the EU.

Source: Estonia Is a ‘Digital Republic’—What That Means and Why It May Be Everyone’s Future

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COVID-19: Intention was to write essays. Gathered data, too much, too manic, then came fear as I read the Harvard notes on how to write an essay. After the last recession 2009; I wrote most days on WordPress. Time is now and I will continue to write in the way I know best, without having to conform …

11th October, 2020

The Qualifier is the essay to me is about perfection and it is perfection that creates the massive anxiety disorder which causes mental collapse.

Every day I start the day by looking for a quotation which engages me with whatever is within that day. I then go to my twitter account @canisgallicus and I “paste” the quote, with a comment added by me to a variety of tweeters who may be interested – these days it mostly relates to COVID-19.

Tweet:

Please COVID-19 has given us “TIME”; let’s take time to examine

our lives; we know 2021 will yield vaccine, but

be learned going forward. Charlie Chaplin –

Final Speech from The Great Dictator

https://youtu.be/J7GY1Xg6X20 via @YouTube

“Fight for world of Reason” Science too.

Pandemic no 2 is mental health; the loss of mental wellness which is happening now but will apply for decades to come.

This was tweet sent out on 10th October 2010 – World Mental Health Day.

Mental Health Crisis in a Knowledge Economy-The Brain Forum Debates 2020 YouTube https://youtube.com/watch?v=z_BJw5oD7w4 2nd pandemic=mental health; it is sequel to COVID-19. Listen to ple who have had mental breakdowns esp Alistair Campbell&Anna Williamson; be ahead of curve. Me Anxiety/Bipolar

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Trump’s COVID infection shows why it’s time to retire the nuclear football – Bulletin of the Atomic Scientists

Allowing the president to retain sole authority—even when he can’t think clearly—increases the risk of blundering into nuclear war.

Source: Trump’s COVID infection shows why it’s time to retire the nuclear football – Bulletin of the Atomic Scientists

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Vaccines don’t save lives. Vaccinations save lives

(2019). Vaccines don’t save lives. Vaccinations save lives. Human Vaccines & Immunotherapeutics: Vol. 15, No. 12, pp. 2786-2789.

Source: Vaccines don’t save lives. Vaccinations save lives

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A Norwegian Startup Is Turning Dry Deserts Into Fertile Cropland

The UN population forecast predicts that by 2050 there will be almost 10 billion people on the planet. They’ll live mostly in cities and have an older median age than the current global population. One looming questions is, what will they eat? The Green Revolution of the 1960s used selective breeding to double crop yields …

Source: A Norwegian Startup Is Turning Dry Deserts Into Fertile Cropland

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“Deaths of Despair and the End of Capitalism” but what was not envisaged was a Pandemic coronavirus known as COVID-19. Since March 17th 2020 we are a world frozen in time but now it is the present and future. How do we go forward? Panorama BBC 1 Cancer Crisis; 35,000 estimated to die.

What can we do to cope?  We can start each day and end each day with a Gratitude List, as suggested by Ariana Huffington, Huffington Post.  It is grounding and never more than now, we need to engage with  life in a positive way realising that COVID-19 has no cure, and it will take probably a year or more to have a vaccine or sera.

A wise old Judge (Michael Comyn KC) once said and this was back in the 1950’s when there was no internet available to most people “Knowledge is no Load”.  What we need to achieve now is to ensure that the digital divide is eradicated and people are encouraged into lifelong learning as the opportunities are available.  If you have no computer at home; there always is the library.  The idea of a Universal Basic Income becomes essential as artificial intelligence, robots, technology, eHealth and so much more, are the future and there may be a reduction in work as we know it.  What is important is creativity and this can be fostered by people who may work but in a different way to others; they are imbibed with a gift or a talent and this is often rooted in the will to improve the lives of others through being creative in thinking and engaged with society through the internet and social media

This week Ireland finally has managed to achieve a new Government after months of negotiations between varying parties.  Fine Gael (Leo Varadkar); Finana Fail (Micheal Martin); the Greens (Eamon Ryan) are in power now.  The Cabinet selection resulted in disappointments for certain truly committed politicians and below is a copy of an email sent to some of them, politicians who I would regard as able and now become the untapped resources of intelligencce and political endeavour with a power to finally dispel corruption which has hindered Ireland which remains a young State, now in its centenary year.

Subject: The Doctor Is In: Scott Atlas and the Efficacy of Lockdowns, Social Distancing, and Closings – YouTube. Halt LockDowns in line with common sense argument.
Date: Wed, 1 Jul 2020 17:07:31 +0100
From: Michelle Clarke <michelleclarke@upcmail.ie>
To: John McGuinness <john.mcguinness@oireachtas.ie>, Eamon Ó Cuiv <eamon.ocuiv@oireachtas.ie>, Jim OCallaghan <jim.ocallaghan@oireachtas.ie>, Thomas Byrne <thomas.byrne@oireachtas.ie>

To those who should have been chosen for Cabinet positions.

Highly recommend this:  Too much negativity surrounds the world and Ireland, being a small open economy is particularly vulnerable to recession.  A little vision as Whitaker and Lemass had at another time after the near 30 years of recession/depression in Ireland when we exported our people in droves (no longer an option).

It will take about 45 minutes to listen to Dr Scott Atlas, Hoover Institution being interviewed by Peter Robinson above but what he says is profound and is about common sense with the reasoning of true cost benefit analysis.

I can’t stress the importance of listening to this interview from the Hoover Institution.  Deaths of Despair* (Sir Angus Deaton, Anne Case) needs to be considered.  Unemployment and I know about this from an earlier life, because it set me on a path of multimorbidities, have profound costs that empirical data will corroborate.  Dr Scott Atlas, you may have heard of him or you may not but if not, what he says makes common sense and especially now as we exit LockDown we must be able to take a view of the glass half full otherwise we will ensure a recession/depression most likely worse than the 1930’s.  Just one example: because retention is not a strong point for my brain … 35% and above of children taken to A&E in America (with severe injuries) are noticed and referred to A&E, in the school system.  Unemployment happens at the lower end of the salary scale and therefore to have no school puts children in serious jeopardy and this is a cost in its own right as distinct from having COVID-19.

*  “Deaths of Despair”:  This is a short interview talking about suicide, addiction, unemployment and how people reach that level of being disconnected from society.  COVID-19 has not even considered this crisis in the making but the time has come to value the lives of people who suffer from Despair.  There will be many casualties over time.  https://www.youtube.com/watch?v=yXf-xcR8bdA

Recommend this link too:  COVID-19 and Lesson from Pandemics (Professor Niall Ferguson) https://www.youtube.com/watch?v=dmmOiG8Odm8

Panorama BBC  1:  No screening for cancer because of COVID-19 priority; so many dying or having worse experiences with cancer as a result of hospitals being closed off and the cancellation of screening, or worse chemotherapy, drugs trials, radiology, being interrupted, is worth watching.  The figure could be as high as 35,000 deaths as a result of COVID-19 priority.

https://www.dailymail.co.uk/femail/article-8493967/BBC-podcaster-Deborah-James-reveals-friend-31-died-cancer-soon-COVID.html

Private treatment under Professor John Crown, Oncology, St Vincent’s Private hospital. My mother paid throughout her life for my VHI cover.  Imagine if it had been through this COVID-19 ominous Pandemic period.  Professor Angus Deaton and Anne Case – Deaths of Despair and the End of Capitalism is recommended.  Poverty, unemployment, illness, violence in the home, hardship are bad cards to be dealt in life.  My treatment went smoothly and I wrote a book logging my experiences which may be interested to those looking at how COVID-19 had impeded their treatment.  Timing is so important.  Too many are not being screened now and nobody is talking about it.  Thank you Panorama because as always you aim to shock people with truth and facts, into a reality they wish to avoid.

My book:

Fortune Favours the Brave by Michelle Marcella Clarke

https://www.amazon.co.uk/Fortune-Favours-Michelle-Marcella-Clarke/dp/1912639610

 

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