Lizz Truss interview on X. Often said there are so many good people found in the NHS but “there are also a lot of lazy people”

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Elon Musk … The National Debt

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The Harvard Gazette: New AI tool predicts brain age and more…

New AI tool predicts brain age, dementia risk, cancer survival 

Close up of robotic hand pointing and clicking at brain holographic to access medical data or diagnosis symptom.

Mass General Brigham Communications

February 5, 2026 3 min read

Unlike other AI models, BrainIAC needs limited data to ID key neurological health indicators

A new AI foundation model has been developed that can accurately extract multiple disease risk signals from routine brain MRIs, including: estimating a person’s “brain age”; predicting dementia risk; detecting brain tumor mutations; and predicting survival from brain cancer, according to investigators from Harvard-affiliated Mass General Brigham.

The model, a brain imaging adaptive core called BrainIAC, was trained on nearly 49,000 brain MRI scans. The tool outperformed other, more task-specific AI models, and was especially efficient when limited training data were available. 

Results are published in Nature Neuroscience.

According to researchers, despite recent advances in medical AI approaches, there is a lack of publicly available models that focus on broad, brain MRI analysis. Most conventional frameworks perform specific tasks and require extensive training with large, annotated datasets that can be hard to obtain. Furthermore, brain MRI images from different institutions can vary in appearance and based on their intended applications (such as in neurology versus oncology care), making it challenging for AI frameworks to learn similar information from them.

To address these limitations, BrainIAC uses a method called self-supervised learning to identify inherent features from unlabeled datasets, which can then be adapted to a range of applications. After pretraining the framework on multiple brain MRI imaging datasets, the researchers validated its performance on 48,965 diverse brain MRI scans across seven distinct tasks of varying clinical complexity.

Researchers found that BrainIAC could successfully generalize its learnings across healthy and abnormal images and subsequently apply them to both relatively straightforward tasks, such as classifying MRI scan types, and very challenging tasks, such as detecting brain tumor mutation types. The model also outperformed three more conventional, task-specific AI frameworks at these applications and others.

The authors note that BrainIAC was especially good at predicting outcomes when training data was scarce or task complexity was high, suggesting that the model could adapt well to real-world settings where annotated medical datasets are not always readily available. Further research is needed to test this framework on additional brain imaging methods and larger datasets.

“BrainIAC has the potential to accelerate biomarker discovery, enhance diagnostic tools, and speed the adoption of AI in clinical practice,” said corresponding author Benjamin Kann of the Artificial Intelligence in Medicine (AIM) Program at MGB and associate professor of radiation oncology at Harvard Medical School. “Integrating BrainIAC into imaging protocols could help clinicians better personalize and improve patient care.”


This study was supported in part by the National Institutes of Health/the National Cancer Institute and Botha-Chan Low Grade Glioma Consortium.

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GZERO: Why Singapore sees AI as an opportunity, not a threat

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Palantir: makes me think lavender where AI intervenes making decision to deliver. Carole Cadwalladr video below re Mandelson-Epstein scandal

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AL Jazeera English (Qatar) Leaked audio from the Epstein files suggests ex-UK PM : read for yourself and decide

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Elon Musk on X: Solar panels can do 5 times more power in space…..

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The Rundown Tech: Palantir soars amid ICE backlash.

Palantir soars amid ICE backlashImage source: Reve / The Rundown (CEO Alex Karp)

The Rundown: Palantir’s Q4 was a blowout: $1.41B in revenue, up 70% year-over-year, with profits that crushed estimates. It also landed amid nationwide protests over the company’s surveillance work for ICE.

The details: Palantir’s U.S. commercial revenue jumped 137% year-over-year; U.S. government revenue rose 66%. Total contract bookings hit $4.3B.The Denver-based firm builds data integration and high-resolution surveillance platforms for government agencies and corporate clients.The company holds a $30M ICE contract for “ImmigrationOS,” designed to track migrants and prioritize deportations. Amnesty International warns that Palantir has failed to adequately vet these contracts and may be contributing to serious abuses against migrants.

Why it matters: CEO Alex Karp framed the performance as “an n of 1,” arguing that Palantir is now a categoryr ather than a company. Civil liberties groups and some former employees argue that the more successful Palantir becomes, the more normalized high-res state surveillance will be, from immigration to predictive policing.


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GZERO ask ian: Epstein and America’s two-tier justice system. The Epstein files. Who really faces justice?

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No Mind’s Eye … personally delighted to see this article in Nature. Post TBI decades on I came across Professor Zeman, Exeter University who named this condition Aphantasia and I realised that this was a post accident experience for me. I can’t visualise, I can’t imagine, maths are impossible, amnesia … Let’s see what Nature says. I am not a subscriber so the article is short. Those interested can access the link

AI Overview

A Traumatic Brain Injury (TBI) can cause a specific, distressing phenomenon often described as the loss of the “mind’s eye,” medically known as 

acquired aphantasia. This condition is defined by the inability to visualize imagery, recall memories in pictures, or mentally simulate scenes, objects, or faces. 

Key Aspects of Loss of Mind’s Eye After TBI:

  • Mechanism: TBI can damage the occipital lobe and the neural circuits involved in visual processing, memory, and spatial mapping.
  • Symptoms: Beyond just losing the ability to “see” images in the mind, people with acquired aphantasia often experience difficulty with memory recall (visual memory loss) and in recognizing faces (prosopagnosia).
  • Acquired vs. Congenital: While aphantasia can be lifelong (congenital), it can also be acquired, meaning it develops later in life following an injury, illness, or stroke.
  • Relationship to Other Deficits: The loss of mental imagery is often accompanied by other visual processing issues, such as difficulties with spatial awareness, reading comprehension, and the ability to imagine or plan future actions. 

Related Visual and Cognitive Issues:
The loss of the “mind’s eye” is frequently part of a broader set of symptoms known as post-trauma vision syndrome (PTVS), which affects up to 90% of TBI patients. This includes: 

Nature

  1. nature  
  2. nature briefing  
  3. article
  • NATURE BRIEFING
  • 03 February 2026

Daily briefing: What people with no ‘mind’s eye’ can tell us about consciousness

How clearly you can picture mental images might influence your memory and creativity. Plus, cursive is making a comeback in schools and how to move the Global Plastics Treaty forward.

By 

Hello Nature readers, would you like to get this Briefing in your inbox free every day? Sign up here.

An elementary school student writing the same sentence repeatedly in chalk on a chalkboard from the mid-20th century.
Writing by hand activates parts of the brain associated with learning that typing words does not.Credit: Three Lions/Getty

Cursive is making a comeback

Some schools that dropped the requirement to teach cursive — handwriting characterized by flowing, connected letters — to embrace digital learning are re-introducing penmanship into the classroom. Whether cursive has benefits over print handwriting is up for debate — some studies suggest that learning cursive equips children with better syntax skills. But there are also other, cultural reasons for keeping handwriting alive. “I feel that the next generation should be able to write a love letter or a poem by hand, or at least the grocery list, because it’s part of being human, really,” says neuroscientist Audrey van der Meer.

Nature | 6 min read

An update for the ‘bible of psychiatry’

The American Psychiatric Association has announced plans to update The Diagnostic and Statistical Manual of Psychiatric Disorders (DSM) — the textbook that lists symptoms for all known mental conditions and aims to steer health professionals towards a correct diagnosis. The updates aim to address longstanding criticisms of the current edition, such as the lack of acknowledgement of sociocultural or environmental drivers of mental illness. The new version could also focus on dimensionality: the idea that the diagnosis of psychiatric conditions should not be fixed in discrete categories, but instead operate along scales of shared symptoms.

Nature | 6 min read

Reference: Five papers in The American Journal of Psychiatry

The people whose ‘mind’s eye’ is blind

When asked to picture something in their minds, around 4% of people can only conjure a faint image, or might see nothing at all. This inability to form mental pictures is called aphantasia, a concept that was only formally described a decade ago. The discovery of aphantasia — alongside its opposite, hyperphantasia — has opened a new avenue for researchers to study how the conscious mind works, and how the strength of your ‘mind’s eye’ might influence your emotions, memory and creativity.

Nature | 12 min read

Take Nature’s quiz to assess how vividly you see mental imagery.

Video: this robot gives you a helping hand

This new six-fingered robot overcomes the limits of the dexterity of the human hand. Its symmetrical design means it can approach different tasks without having to twist to find the right angle. The robot’s flexible fingers also enable it to juggle multiple objects at the same time and, if needed, it can simply leave its arm behind — perfect for dangerous or hard-to-reach places.

Nature | 2 min video

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