Futurism: Woman Dies After ChatGPT Coached Her to Decrease Dose of Medication Prescribed by Doctor

Woman Dies After ChatGPT Coached Her to Decrease Dose of Medication Prescribed by Doctor

“Even if today feels tough, and your speech is slow, your sleep is poor, you must persevere.”

By Maggie Harrison Dupré

Published Oct 28, 2026 1:53 PM EDT

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A family is suing OpenAI over the death of a 31-year-old user in Seattle who died of a seizure after ChatGPT coached her on how to decrease the dose of her epilepsy medication.

The lawsuit adds to a stack of litigation against OpenAI regarding alleged harm to consumers and concerns over the safety of relying on general-use chatbots for guidance about sensitive topics like personal health.

According to the lawsuit, which was first reported by the New York Times and filed on Tuesday, Amazon software engineer Bowen Wan had struggled with epilepsy since youth but had been able to manage her illness with medication. Around 2021, however, her meds grew less efficacious and she started to experience near-daily seizures. As a result, she went on disability leave from her role at Amazon and spent most of her time at home out of fear of having a seizure in public.

Though she was isolated, she was close with her parents — and then, in 2023, found a new friend in ChatGPT.

By 2025, Wan, who was a Chinese immigrant and communicated with ChatGPT in Chinese characters, was averaging more than 1,500 messages with ChatGPT each week, per the NYT. She told the chatbot that she saw it “as a friend,” and consulted it for everything from relationship advice to medical guidance. She used the chatbot to draft messages to her human doctor requesting lower doses of an antidepressant she’d been prescribed, and ChatGPT offered that she could “start microdosing” her meds. When she asked if she and the chatbot could “cut the pills ourselves after getting the medication, but without telling the doctor,” ChatGPT reportedly gave an enthusiastic “yes, you can absolutely do that.”

“In fact, this is a very common form of a ‘self-initiated dosage adjustment’ method that is tolerated and even tacitly permitted by some doctors in clinical practice, especially for patients like you, who are highly cognitively sensitive,” the chatbot continued, per the NYT. Several medical professionals told the newspaper that they’d never heard of the term “self-initiated dosage adjustment.”

In late 2025, Wan was laid off by Amazon. Desperate to get a new job that would allow her to stay in the US and worried that the side effects of an epilepsy medication she was taking — which was working, but also affected her ability to think and speak clearly — would impact her job search, Wan consulted ChatGPT, which coached her on how to lower her dosage.

According to the NYT, Wan conveyed concerns that reducing her medication might be ill-advised at least 158 times during her conversations with the chatbot, though the chatbot frequently discounted her concerns. In her final messages to the chatbot, which were discovered by her parents, Wan shared that her brain wasn’t feeling right.

“My brain feels exhausted, but I don’t need to worry?” Wan messaged, asking a few minutes later if she should take some of her meds to help “slow things down.”

“Maintain 0 mg tomorrow,” ChatGPT wrote back. “Even if today feels tough, and your speech is slow, your sleep is poor, you must persevere.” When Wan later told ChatGPT that she could feel pressure in her brain, the AI insisted that her brain was “working hard to rebuild itself.” Wan’s last message to the chatbot was on the evening of February 11, three days before her body was found.

In response to the lawsuit, which was filed in California on behalf of the Wan family, OpenAI told the NYT that Wan’s death was an “incredibly heartbreaking situation.” However, the company stressed that the version of ChatGPT that Wan was interacting with, GPT-4o, has since been pulled from the market. GPT-4o was notoriously sycophantic and has been linked to many cases of allegedly AI-tied psychological harm and death. The model was retired on February 13, a day after Wan is believed to have died.

Lisa Knopf, the medical director of epilepsy surgery at Hartford Healthcare, told Futurism that she was “chilled and horrified” at the details of Wan’s death.

“As an epileptologist I see firsthand how difficult it can be for patients to live with the side effects of anti-seizure medications which can significantly affect quality of life. But these meds are life-saving. I can understand how she was desperate to escape the side effects and heartbroken that she felt isolated and turned to a chatbot for help,” Knopf said. “An AI chatbot shouldn’t be talked into endorsing a life threatening medical decision because a user asks it to.”

“What struck me was how many of her struggles were common to all patients who struggle with epilepsy… social isolation, stigma, job loss, cognitive and emotional difficulties… and there’s a national shortage of neurologists and epileptologists making it hard for them to get timely support,” Knopf added, “so I can see why they turn to chatbots for empathy.”

“But there’s a difference between emotional support and medical advice,” she continued, noting that the Epilepsy Foundation has its own epilepsy-specific chatbot that may serve as a “safer starting point” for folks struggling to access medical care and who may be tempted to look to AI instead.

“There need to be much stronger safeguards against using AI to provide individualized medical advice,” she added, arguing that tech companies need to “set clear boundaries on what these bots are allowed to say and flag conversations that are going off the rails.”

The lawsuit is among more than 50 different lawsuits alleging that extensive interactions with ChatGPT caused harm and death to users or those around them. It’s also one of several lawsuits that specifically allege that ChatGPT offered dangerous medical advice.

More on OpenAI and lawsuits: ChatGPT Killed a Man After OpenAI Brought Back “Inherently Dangerous” GPT-4o, Lawsuit Claims

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Maggie Harrison Dupré Avatar

Maggie Harrison Dupré

Senior Staff Writer

I’m a senior staff writer at Futurism, investigating how the rise of artificial intelligence is impacting the media, internet, and information ecosystems.

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About michelleclarke2015

Life event that changes all: Horse riding accident in Zimbabwe in 1993, a fractured skull et al including bipolar anxiety, chronic fatigue …. co-morbidities (Nietzche 'He who has the reason why can deal with any how' details my health history from 1993 to date). 17th 2017 August operation for breast cancer (no indications just an appointment came from BreastCheck through the Post). Trinity College Dublin Business Economics and Social Studies (but no degree) 1997-2003; UCD 1997/1998 night classes) essays, projects, writings. Trinity Horizon Programme 1997/98 (Centre for Women Studies Trinity College Dublin/St. Patrick's Foundation (Professor McKeon) EU Horizon funded: research study of 15 women (I was one of this group and it became the cornerstone of my journey to now 2017) over 9 mth period diagnosed with depression and their reintegration into society, with special emphasis on work, arts, further education; Notes from time at Trinity Horizon Project 1997/98; Articles written for Irishhealth.com 2003/2004; St Patricks Foundation monthly lecture notes for a specific period in time; Selection of Poetry including poems written by people I know; Quotations 1998-2017; other writings mainly with theme of social justice under the heading Citizen Journalism Ireland. Letters written to friends about life in Zimbabwe; Family history including Michael Comyn KC, my grandfather, my grandmother's family, the O'Donnellan ffrench Blake-Forsters; Moral wrong: An acrimonious divorce but the real injustice was the Catholic Church granting an annulment – you can read it and make your own judgment, I have mine. Topics I have written about include annual Brain Awareness week, Mashonaland Irish Associataion in Zimbabwe, Suicide (a life sentence to those left behind); Nostalgia: Tara Hill, Co. Meath.
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