AI Interviews Outperform Standard Mental Health Rating Scales. Comment: as a person with mental illness (depression, anxiety, compulsivity) I can see great potential here. Ireland and mental illness is in the wilderness and people who could be treated while still young but the waiting lists are too long, are destined for a life of grave discomfort for all. There are many parents now afraid of their adult children who have mental illness. FT did an article on this last weekend.

Featured Neuroscience Psychology

·November 20, 2025

Summary: A new study demonstrates that an AI assistant can conduct psychiatric assessment interviews with greater diagnostic accuracy than widely used mental health rating scales. In a sample of 303 participants with confirmed psychiatric conditions, the AI assistant Alba provided DSM-based diagnostic suggestions after a brief conversational interview, outperforming rating scales in eight of nine disorders.

Alba was particularly effective at distinguishing conditions that often overlap, such as depression and anxiety, which traditional scales frequently score similarly. Participants also reported positive user experiences, indicating that conversational AI may offer a scalable, person-centered tool to support clinical assessment while preserving the clinician’s essential role.

Key Facts:

• Higher Accuracy: AI-based interviews outperformed standard rating scales in diagnosing eight of nine psychiatric conditions.
• Better Differentiation: Alba more clearly distinguished between overlapping symptoms such as anxiety and depression.
• Positive Experience: Participants reported the AI interview felt empathic, supportive, and engaging.

Source: Lund University

A new study shows that an AI assistant can conduct assessment conversations with patients with higher accuracy than the rating scales used in healthcare today. In the study, 303 participants were interviewed by the AI ​​assistant Alba, who then suggested possible psychiatric diagnoses.

In addition to being interviewed by an AI assistant, the participants also had to fill out standardized rating scales for the nine most common psychiatric diagnoses.

The results showed that the AI ​​assistant’s assessments were more consistent with the participants’ actual diagnoses than the rating scales did.

The study included individuals with confirmed diagnoses for conditions such as depression, anxiety, obsessive-compulsive disorder, PTSD, ADHD, autism, eating disorders, substance use disorder and bipolar disorder, as well as a control group.

All participants had an online interview with the AI assistant, Alba, which asked 15-20 open questions about their mental health and then proposed diagnoses based on DSM-5 – the internationally-used manual for psychiatric diagnosis.

The AI assistant achieved higher accuracy in eight of the nine diagnoses, and could differentiate more clearly between diagnoses that often overlap. For example, the conventional rating scales often gave similar readings for depression and anxiety, whereas Alba’s assessments could discern the conditions more clearly.

The participants also described the user experience as positive – many perceived the AI assistant as empathic, relevant and supportive.

“An interview that can be done in a safe home environment before meeting a clinician has great value. The results point to a scalable, person-centred complement that can lighten the load for healthcare and provide a preliminary assessment, without replacing  the psychologist or physician,” says Professor of Psychology Sverker Sikström, leader of the research team behind the study at Lund University and founder of the company, Talk To Alba.

Analyses the entire diagnostic manual – not just individual conditions

According to Sverker Sikström, the study marks a clear step forward in research on digital assessment tools for mental health. Previous studies have often been confined to analysing individual diagnoses or lacked clear justifications based on diagnostic criteria, whereas Alba can propose and justify all the diagnoses included in the DSM manual.

Fact box: What is Talk To Alba?

Talk To Alba is an online-based AI tool for the assessment, treatment and administration of mental health for professionals (psychologists, psychiatrists and physicians) who work in the area.

The tool includes AI-powered clinical interviews and CBT for patients, automatic diagnosis of mental health justified in accordance with DSM-5, informed AI dialogues about patients for clinics, and the transcribing and journal note-taking of patient meetings.

Alba, which is used at clinics in Sweden and abroad, is owned by TalkToAlba AB. 

Key Questions Answered:

Q: Can an AI interview detect psychiatric conditions more accurately than rating scales?

A: Yes. The AI assistant showed higher diagnostic accuracy than standardized scales in eight of nine conditions.

Q: Does the AI differentiate between overlapping conditions effectively?

A: It does. Alba separated diagnoses like anxiety and depression more clearly than conventional tools.

Q: How did participants respond to the AI-led interviews?

A: Most described the experience as empathic, relevant, and supportive.

Editorial Notes:

• This article was edited by a Neuroscience News editor.
• Journal paper reviewed in full.
• Additional context added by our staff.

About this AI and mental health research news

Author: Lotte Billing
Source: Lund University
Contact: Lotte Billing – Lund University
Image: The image is credited to Neuroscience News