Neuroscience News (@NeuroscienceNew) posted at 7:31 pm on Fri, Nov 15, 2024:
How Stressful Events Alter Memories
Stress can disrupt memory precision, leading to generalized aversive memories that trigger fear in unrelated, safe situations—a hallmark of PTSD.
Researchers found that stress increases the release of endocannabinoids, which enlarges memory…
How Stressful Events Alter Memories
Stress can disrupt memory precision, leading to generalized aversive memories that trigger fear in unrelated, safe situations—a hallmark of PTSD. Researchers found that stress increases the release of endocannabinoids, which enlarges memory engrams in the brain by disrupting interneurons responsible for maintaining engram specificity. These larger engrams cause generalized fearful memories, impairing the ability to distinguish between threatening and safe environments. By blocking endocannabinoid receptors on specific interneurons, researchers were able to restore memory specificity and limit the spread of fearful responses. This breakthrough sheds light on the biological mechanisms of stress-induced memory generalization and offers a promising pathway for PTSD treatment. Future research will explore links between memory engrams, stress, and age to further refine therapeutic approaches.
https://t.co/QjQR90lcWx
(https://x.com/NeuroscienceNew/status/1857506623704674432?t=eILxg20bzLPyQ1d-_C3whw&s=03)
About michelleclarke2015
Life event that changes all: Horse riding accident in Zimbabwe in 1993, a fractured skull et al including bipolar anxiety, chronic fatigue …. co-morbidities (Nietzche 'He who has the reason why can deal with any how' details my health history from 1993 to date). 17th 2017 August operation for breast cancer (no indications just an appointment came from BreastCheck through the Post). Trinity College Dublin Business Economics and Social Studies (but no degree) 1997-2003; UCD 1997/1998 night classes) essays, projects, writings. Trinity Horizon Programme 1997/98 (Centre for Women Studies Trinity College Dublin/St. Patrick's Foundation (Professor McKeon) EU Horizon funded: research study of 15 women (I was one of this group and it became the cornerstone of my journey to now 2017) over 9 mth period diagnosed with depression and their reintegration into society, with special emphasis on work, arts, further education; Notes from time at Trinity Horizon Project 1997/98; Articles written for Irishhealth.com 2003/2004; St Patricks Foundation monthly lecture notes for a specific period in time; Selection of Poetry including poems written by people I know; Quotations 1998-2017; other writings mainly with theme of social justice under the heading Citizen Journalism Ireland. Letters written to friends about life in Zimbabwe; Family history including Michael Comyn KC, my grandfather, my grandmother's family, the O'Donnellan ffrench Blake-Forsters; Moral wrong: An acrimonious divorce but the real injustice was the Catholic Church granting an annulment – you can read it and make your own judgment, I have mine. Topics I have written about include annual Brain Awareness week, Mashonaland Irish Associataion in Zimbabwe, Suicide (a life sentence to those left behind); Nostalgia: Tara Hill, Co. Meath.
canisgallicus 